OUR EXTRACTION METHODS
As experts in cannabinoid medicine, having treated thousands of patients with remarkable results, we are absolutely convinced that CannaKoru is among the most effective and bioavailable CBD oil on the market. Our hemp is organically cultivated on a pesticide-free farm in Boulder, CO, and is extracted using either nanoemulsified and/or solventless methods that isolate and preserve the terpenes and cannabinoids.
The power of Intravenous Therapy in a Convenient Oral Liposomal Delivery with our CannaKoru 400mg Nanoemulsified Citrus CBD Tincture.
Liposomes are microscopic single to multilayer spheres made of phospholipids (the basic building blocks of cell membranes). Phospholipids encapsulate a compound, such as CBD, in order to bypass the digestive processes that normally degrade or limit the compound's absorption. Liposomes demonstrate the ability to cross the blood-brain barrier, deposit their cargo intracellularly, and enhance lymphatic circulation of therapeutic compounds.
Additionally, the phospholipids that compose the liposome fuse with and feed the cell membranes. Providing phospholipids in this way ensures proper membrane function to facilitate the absorption of nutrients and the excretion of cellular waste products and toxins. In fact, phospholipid therapy, using both injectable forms and oral forms, has a long and solid clinical history for repair and maintenance of liver function, circulatory health, and neurological health.
At their highest expression, liposomes bring the power of intravenous therapy into a convenient oral delivery. However, all liposomes are not created equally. Most liposomes on the market use low grades of phospholipids, e.g. raw lecithin, instead of the high-phosphatidylcholine phospholipid mixes necessary for a good liposome. Nutraceutical manufacturers also typically use cheap shear methods resulting in large (200–600nm), poorly-absorbed particles.
This is why we collaborated with Dr. Chris Shade at Quicksilver Scientific who has improved upon basic liposomal delivery technology with smaller, more stable, tightly distributed single-layer spheres (called unilamellar vesicles) made from the highest-grade ingredients available. These small vesicles begin absorbing as soon as they hit your mouth, so you can get high absorption before they are altered by the harsh processes in the intestines. Quicksilver Scientific uses the same high-tech equipment, rigorous processes, and tight particle size controls used by pharmaceutical companies.
But don't take our word for it, the Quicksilver Scientific Nanoemulsified uptake studies are backed by The University of Maryland and National Institute of Standards and Technology studies.*
*Pharmacy-On-A-Chip: Microfluidic Synthesis of Pegylated and Folate Receptor-Targeted Liposomes For Drug Delivery.
*Shade C., Liposomes as Advanced Delivery Systems for Nutraceuticals. Integr Med (Encinitas). 2016 Mar;15(1):33-6.
ABOUT SOLVENTLESS EXTRACTION
All our CannaKoru capsules and topicals use organically cultivated hemp from Boulder Hemp Farms, and is extracted using a proprietary solventless extraction method.
*The benefit of solventless extracted hemp is that it is minimally processed with cold temperatures to isolate the most active parts of the hemp plant (the glandular trichomes) from the plant material. This results in highly concentrated products that contain approximately 90% of the active cannabinoids, essential oils, and terpenoid components. Microscopy, third-party lab tests, chromatography, and several other methods of examination are employed to assure the true condition of our extraction method. We also post those third-party certificates of analysis tests for all our products on our COA page.
We grow all of our hemp in Boulder County, Colorado at an elevation of 4,995 feet above sea level, using strictly organic cultivation practices at Boulder Hemp Farm.
SMALL BATCH CRAFTING
All CBD products are carefully crafted in small batches, using a science driven approach, and tested by multiple independent labs for purity and potency.
SEEDS AND SEEDLINGS
Every plant starts as a seed. Large scale hemp production is not possible without a consistent high-quality seed supply. Boulder Hemp Farm has been researching and breeding seed lines in Colorado since 2014.
HIGH-INTENSITY PESTICIDE-FREE AGRICULTURE
Boulder Hemp Farm uses only pesticide-free growing practices ensuring a pure extract of the highest quality.
*Gold, D. 1973. Cannabis Alchemy-The art of modern hasmaking: Methods for preparation of extremely potent cannabis products. Berkeley, CA: Ronin.
*Clarke, R.C. 1998. Hashish. Los Angeles, CA: Red Eye Press
*Gould, J. 2001. Personal Communication. THC Pharm, Frankfurt, Germany.